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Current mouse models of oral squamous cell carcinoma: Genetic and chemically induced models

20 Sept 2017

Abstract excerpt

Oral squamous cell carcinoma (OSCC) patients have a low 5-year survival rate and poor prognosis. To improve survival and prognosis, the causes and processes involved in lesion development should be evaluated. For this purpose, the use of OSCC mouse models, such as chemically induced mouse models, genetically modified mouse models, and transplanted (xenograft) models, is crucial. These OSCC models exhibit both...

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PMID: 28939069
DOI: 10.1016/j.oraloncology.2017.07.028

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