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Article

Proteomic Features of Colorectal Cancer Identify Tumor Subtypes Independent of Oncogenic Mutations and Independently Predict Relapse-Free Survival.

Annals of surgical oncology - 1 Dec 2017

Clarke Callisia N, Lee Michael S, Wei Wei, Manyam Ganiraju, Jiang Zhi-Qin, Lu Yiling, Morris Jeffrey, Broom Bradley, Menter David, Vilar-Sanchez Eduardo, Raghav Kanwal, Eng Cathy, Chang George J, Simon Iris, Bernards Rene, Overman Michael, Mills Gordon B, Maru Dipen, Kopetz Scott

Abstract excerpt

BACKGROUND: The directed study of the functional proteome in colorectal cancer (CRC) has identified critical protein markers and signaling pathways; however, the prognostic relevance of many of these proteins remains unclear. METHODS: We determined the prognostic implications of the functional proteome in 263 CRC tumor samples from patients treated at MD Anderson Cancer Center (MDACC) and 462 patients from The...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 28936799
DOI: 10.1245/s10434-017-6054-5
PMCID: PMC6063735

Genes

PEA15

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