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Article

Prognostic implications of an autophagy-based signature in colorectal cancer

31 Mar 2021

Abstract excerpt

BACKGROUND: The heterogeneity of colorectal cancer (CRC) poses a significant challenge to the precise treatment of patients. CRC has been divided into 4 consensus molecular subtypes (CMSs) with distinct biological and clinical characteristics, of which CMS4 has the mesenchymal identity and the highest relapse rate. Autophagy plays a vital role in CRC development and therapeutic response. METHODS: The gene...

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PMID: 33787596
DOI: 10.1097/md.0000000000025148

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