Article
Metabolic status of CSF distinguishes rats with tauopathy from controls.
Alzheimer's research & therapy - 21 Sept 2017
Karlíková Radana, Mičová Kateřina, Najdekr Lukáš, Gardlo Alžběta, Adam Tomáš, Majerová Petra, Friedecký David, Kováč Andrej
Abstract excerpt
BACKGROUND: Tauopathies represent heterogeneous groups of neurodegenerative diseases that are characterised by abnormal deposition of the microtubule-associated protein tau. Alzheimer's disease is the most prevalent tauopathy, affecting more than 35 million people worldwide. In this study we investigated changes in metabolic pathways associated with tau-induced neurodegeneration. METHODS: Cerebrospinal fluid...
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