Article
Comparative genetic analyses point to HCP5 as susceptibility locus for HCV-associated hepatocellular carcinoma.
Journal of hepatology - 1 Sept 2013
Lange Christian M, Bibert Stéphanie, Dufour Jean-François, Cellerai Cristina, Cerny Andreas, Heim Markus H, Kaiser Laurent, Malinverni Raffaele, Müllhaupt Beat, Negro Francesco, Semela David, Moradpour Darius, Kutalik Zoltán, Bochud Pierre-Yves
Abstract excerpt
BACKGROUND & AIMS: Recently, genetic variations in MICA (lead single nucleotide polymorphism [SNP] rs2596542) were identified by a genome-wide association study (GWAS) to be associated with hepatitis C virus (HCV)-related hepatocellular carcinoma (HCC) in Japanese patients. In the present study, we sought to determine whether this SNP is predictive of HCC development in the Caucasian population as well. METHODS:...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
