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Mutations in BRAF codons 594 and 596 predict good prognosis in melanoma

19 Jul 2017

Abstract excerpt

B-Raf proto-oncogene serine/threonine kinase (BRAF) V600E is the most common kinase-activating mutation and is associated with poor prognosis in melanoma. However, the clinical significance of kinase-impairing mutations remains unclear. The present study aimed to analyze kinase-impairing mutations in BRAF codons 594 and 596 in non-Caucasian patients with melanoma and to investigate their possible clinical...

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Identifiers

PMID: 28927118
DOI: 10.3892/ol.2017.6608

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