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Article

Whole-genome sequencing illuminates the evolution and spread of multidrug-resistant tuberculosis in Southwest Nigeria.

PloS one - 1 Jan 2017

Senghore Madikay, Otu Jacob, Witney Adam, Gehre Florian, Doughty Emma L, Kay Gemma L, Butcher Phillip, Salako Kayode, Kehinde Aderemi, Onyejepu Nneka, Idigbe Emmanuel, Corrah Tumani, de Jong Bouke, Pallen Mark J, Antonio Martin

Abstract excerpt

Nigeria has an emerging problem with multidrug-resistant tuberculosis (MDR-TB). Whole-genome sequencing was used to understand the epidemiology of tuberculosis and genetics of multi-drug resistance among patients from two tertiary referral centers in Southwest Nigeria. In line with previous molecular epidemiology studies, most isolates of Mycobacterium tuberculosis from this dataset belonged to the Cameroon clade...

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Identifiers

PMID: 28926571
DOI: 10.1371/journal.pone.0184510
PMCID: PMC5604961

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Source receipt: pubmed, retrieved 7 Sept 2026.

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