Article
Multidrug-resistant patients receiving treatment in Niger who are infected with M. tuberculosis Cameroon family convert faster in smear and culture than those with M. tuberculosis Ghana family.
Tuberculosis (Edinburgh, Scotland) - 1 May 2020
Ejo Mebrat, Hassane-Harouna Souleymane, Souleymane Mahamadou Bassirou, Lempens Pauline, Dockx Jeroen, Uwizeye Cecile, De Rijk Pim, Decroo Tom, Diro Ermias, Torrea Gabriela, Rigouts Leen, Piubello Alberto, de Jong Bouke C
Abstract excerpt
In this study, we analyzed the M. tuberculosis complex (MTBc) population structure among multidrug-resistant TB (MDR-TB) patients in Niger and tested whether the Cameroon family displayed a slower response to MDR-TB treatment. We genotyped baseline clinical isolates that had been collected from pulmonary MDR-TB patients recruited consecutively between 2008 and 2016 in Niger. Spoligotyping was used to analyze the...
Topics
- Antitubercular Agents
- Bacteriological Techniques
- Black People
- Cameroon
- Genotype
- Ghana
- Humans
- Mycobacterium tuberculosis
- Niger