Article
Genotypic diversity and drug susceptibility patterns among M. tuberculosis complex isolates from South-Western Ghana.
PloS one - 1 Jan 2011
Yeboah-Manu Dorothy, Asante-Poku Adwoa, Bodmer Thomas, Stucki David, Koram Kwadwo, Bonsu Frank, Pluschke Gerd, Gagneux Sebastien
Abstract excerpt
OBJECTIVE: The aim of this study was to use spoligotyping and large sequence polymorphism (LSP) to study the population structure of M. tuberculosis complex (MTBC) isolates. METHODS: MTBC isolates were identified using standard biochemical procedures, IS6110 PCR, and large sequence polymorphisms. Isolates were further typed using spoligotyping, and the phenotypic drug susceptibility patterns were determined by...
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