Article
Molecular epidemiology of drug resistant Mycobacterium tuberculosis in Africa: a systematic review.
BMC infectious diseases - 13 May 2020
Chisompola Namaunga Kasumu, Streicher Elizabeth Maria, Muchemwa Chishala Miriam Kapambwe, Warren Robin Mark, Sampson Samantha Leigh
Abstract excerpt
BACKGROUND: The burden of drug resistant tuberculosis in Africa is largely driven by the emergence and spread of multidrug resistant (MDR) and extensively drug resistant (XDR) Mycobacterium tuberculosis strains. MDR-TB is defined as resistance to isoniazid and rifampicin, while XDR-TB is defined as MDR-TB with added resistance to any of the second line injectable drugs and any fluoroquinolone. The highest burden...
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