Article
Common variants in DLG1 locus are associated with non-syndromic cleft lip with or without cleft palate.
Clinical genetics - 1 Apr 2018
Mostowska A, Gaczkowska A, Żukowski K, Ludwig K U, Hozyasz K K, Wójcicki P, Mangold E, Böhmer A C, Heilmann-Heimbach S, Knapp M, Zadurska M, Biedziak B, Budner M, Lasota A, Daktera-Micker A, Jagodziński P P
Abstract excerpt
Non-syndromic cleft lip with or without cleft palate (nsCL/P) is a common craniofacial anomaly with a complex and heterogeneous aetiology. Knowledge regarding specific genetic factors underlying this birth defect is still not well understood. Therefore, we conducted an independent replication analysis for the top-associated variants located within the DLG1 locus at chromosome 3q29, which was identified as a novel...
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