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Article

Association of CDKAL1 nucleotide variants with the risk of non-syndromic cleft lip with or without cleft palate.

Journal of human genetics - 1 Apr 2018

Gaczkowska Agnieszka, Żukowski Kacper, Biedziak Barbara, Hozyasz Kamil K, Wójcicki Piotr, Zadurska Małgorzata, Budner Margareta, Lasota Agnieszka, Szponar-Żurowska Anna, Jagodziński Paweł P, Mostowska Adrianna

Abstract excerpt

Although the aetiology of non-syndromic cleft lip with or without cleft palate (nsCL/P) has been studied extensively, knowledge regarding the role of genetic factors in the pathogenesis of this common craniofacial anomaly is still limited. We conducted a follow-up association study to confirm that CDKAL1 nucleotide variants identified in our genome-wide association study (GWAS) for nsCL/P are associated with the...

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Identifiers

PMID: 29403086
DOI: 10.1038/s10038-017-0397-4

Genes

CDKAL1
SOX4

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