Article
Genome-wide compound heterozygote analysis highlights alleles associated with adult height in Europeans.
Human genetics - 1 Nov 2017
Zhong Kaiyin, Zhu Gu, Jing Xiaoxi, Hendriks A Emile J, Drop Sten L S, Ikram M Arfan, Gordon Scott, Zeng Changqing, Uitterlinden Andre G, Martin Nicholas G, Liu Fan, Kayser Manfred
Abstract excerpt
Adult height is the most widely genetically studied common trait in humans; however, the trait variance explainable by currently known height-associated single nucleotide polymorphisms (SNPs) identified from the previous genome-wide association studies (GWAS) is yet far from complete given the high heritability of this complex trait. To exam if compound heterozygotes (CH) may explain extra height variance, we...
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