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Article

The relative contribution of DNA methylation and genetic variants on protein biomarkers for human diseases.

PLoS genetics - 1 Sept 2017

Ahsan Muhammad, Ek Weronica E, Rask-Andersen Mathias, Karlsson Torgny, Lind-Thomsen Allan, Enroth Stefan, Gyllensten Ulf, Johansson Åsa

Abstract excerpt

Associations between epigenetic alterations and disease status have been identified for many diseases. However, there is no strong evidence that epigenetic alterations are directly causal for disease pathogenesis. In this study, we combined SNP and DNA methylation data with measurements of protein biomarkers for cancer, inflammation or cardiovascular disease, to investigate the relative contribution of genetic...

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Identifiers

PMID: 28915241
DOI: 10.1371/journal.pgen.1007005
PMCID: PMC5617224

Genes

CXCL11
CXCL9
NLRC5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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