Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Associations of DNA methylation estimators of protein abundance with concurrent and future physical health risk factors.

Scientific reports - 10 Dec 2025

Waterfield Scott, Yousefi Paul, Suderman Matthew

Abstract excerpt

DNA methylation (DNAm) is an epigenetic modification which plays a role in gene regulation and has genetic and environmental influences. Recently, DNAm-based models of protein abundance (termed episcores) have been developed and were found to be associated with incident disease in older adults. Here, we ask if these episcores are associated with latent physical health phenotypes in children and young adults in...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Child
Share to Cross-Sectional Studies
Share to DNA Methylation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Epigenesis, Genetic

Share to Longitudinal Studies

Share to Mendelian Randomization Analysis

Share to Phenotype

Share to Risk Factors

Source

Open in PubMed Open full text

Identifiers

PMID: 41372382
DOI: 10.1038/s41598-025-31843-z
PMCID: PMC12808646

Genes

CHIT1
SEMA3E

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Associations of DNA methylation estimators of protein abundance with concurrent and future physical health risk factors.PMID 41372382Read ↗

DNA methylation models of protein abundance across the lifecourseSemantic proximity Read ↗

DNA methylation models of protein abundance across the lifecourse.Semantic proximity Read ↗

Epigenetic scores for the circulating proteome as tools for disease predictionSemantic proximity Read ↗

Blood-based epigenome-wide analyses of chronic low-grade inflammation across diverse population cohortsSemantic proximity Read ↗

A novel framework to build saliva-based DNA methylation biomarkers: quantifying systemic chronic inflammation as a case studySemantic proximity Read ↗

The relative contribution of DNA methylation and genetic variants on protein biomarkers for human diseases.Semantic proximity Read ↗

Epigenetic Contributions to Clinical Risk Prediction of Cardiovascular DiseaseSemantic proximity Read ↗

An overview of DNA methylation-derived trait score methods and applications.Semantic proximity Read ↗

Circulating levels of inflammatory markers and DNA methylation, an analysis of repeated samples from a population based cohortSemantic proximity Read ↗

A novel DNA methylation-based surrogate biomarker for chronic systemic inflammation (InfLaMeS): results from the Health and Retirement StudySemantic proximity Read ↗

DNA methylation biomarkers of future health outcomes in childrenSemantic proximity Read ↗

Longitudinal prediction of DNA methylation to forecast epigenetic outcomesSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.