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Article

Exome array analysis identifies ETFB as a novel susceptibility gene for anthracycline-induced cardiotoxicity in cancer patients.

Breast cancer research and treatment - 1 Jan 2018

Ruiz-Pinto Sara, Pita Guillermo, Martín Miguel, Alonso-Gordoa Teresa, Barnes Daniel R, Alonso María R, Herraez Belén, García-Miguel Purificación, Alonso Javier, Pérez-Martínez Antonio, Cartón Antonio J, Gutiérrez-Larraya Federico, García-Sáenz José A, Benítez Javier, Easton Douglas F, Patiño-García Ana, González-Neira Anna

Abstract excerpt

PURPOSE: Anthracyclines are widely used chemotherapeutic drugs that can cause progressive and irreversible cardiac damage and fatal heart failure. Several genetic variants associated with anthracycline-induced cardiotoxicity (AIC) have been identified, but they explain only a small proportion of the interindividual differences in AIC susceptibility. METHODS: In this study, we evaluated the association of...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 28913729
DOI: 10.1007/s10549-017-4497-9

Genes

ETFB

Variants

rs79338777

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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