Article
Secretory phospholipase A2-IIA overexpressing mice exhibit cyclic alopecia mediated through aberrant hair shaft differentiation and impaired wound healing response.
Scientific reports - 14 Sept 2017
Chovatiya Gopal L, Sarate Rahul M, Sunkara Raghava R, Gawas Nilesh P, Kala Vineet, Waghmare Sanjeev K
Abstract excerpt
Secretory phospholipase A2 Group-IIA (sPLA2-IIA) is involved in lipid catabolism and growth promoting activity. sPLA2-IIA is deregulated in many pathological conditions including various cancers. Here, we have studied the role of sPLA2-IIA in the development of cyclic alopecia and wound healing response in relation to complete loss of hair follicle stem cells (HFSCs). Our data showed that overexpression of...
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