Article
ROS induced distribution of mitochondria to filopodia by Myo19 depends on a class specific tryptophan in the motor domain.
Scientific reports - 14 Sept 2017
Shneyer Boris I, Ušaj Marko, Wiesel-Motiuk Naama, Regev Ronit, Henn Arnon
Abstract excerpt
The role of the actin cytoskeleton in relation to mitochondria function and dynamics is only recently beginning to be recognized. Myo19 is an actin-based motor that is bound to the outer mitochondrial membrane and promotes the localization of mitochondria to filopodia in response to glucose starvation. However, how glucose starvation induces mitochondria localization to filopodia, what are the dynamics of this...
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