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Article

MEFV E148Q polymorphism is associated with Henoch-Schönlein purpura in Chinese children.

Pediatric nephrology (Berlin, Germany) - 1 Oct 2010

He Xuelian, Lu Hao, Kang Shixiu, Luan Jiangwei, Liu Zhisheng, Yin Wei, Yao Hui, Ding Yan, Li Tao, Heng Chew-Kiat

Abstract excerpt

Henoch-Schönlein purpura (HSP) is a multifactorial inflammatory disease whose pathogenesis remains unknown. Pyrin encoded by the MEFV gene (NM_000243; OMIM 608107) is an important active member of the inflammasome and has been shown to affect the expression of many of the genes involved in immune and inflammatory responses. The aim of our study was to elucidate the possible roles of MEFV genetic variants on the...

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PMID: 20602240
DOI: 10.1007/s00467-010-1582-2

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MEFV

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

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