Article
Profiling of the metabolic transcriptome via single molecule molecular inversion probes.
Scientific reports - 12 Sept 2017
de Bitter Tessa, van de Water Carlijn, van den Heuvel Corina, Zeelen Carolien, Eijkelenboom Astrid, Tops Bastiaan, Oosterwijk Egbert, Kolev Dimitar, Mulders Peter, Ter Laan Mark, van Lith Sanne, Leenders William
Abstract excerpt
Cancer-specific metabolic alterations are of high interest as therapeutic targets. These alterations vary between tumor types, and to employ metabolic targeting to its fullest potential there is a need for robust methods that identify candidate targetable metabolic pathways in individual cancers. Currently, such methods include 13C-tracing studies and mass spectrometry/ magnetic resonance spectroscopic imaging....
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.