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Article

New prognostic factor telomerase reverse transcriptase promotor mutation presents without MR imaging biomarkers in primary glioblastoma.

Neuroradiology - 1 Dec 2017

Ersoy Tunc F, Keil Vera C, Hadizadeh Dariusch R, Gielen Gerrit H, Fimmers Rolf, Waha Andreas, Heidenreich Barbara, Kumar Rajiv, Schild Hans H, Simon Matthias

Abstract excerpt

PURPOSE: Magnetic resonance (MR) imaging biomarkers can assist in the non-invasive assessment of the genetic status in glioblastomas (GBMs). Telomerase reverse transcriptase (TERT) promoter mutations are associated with a negative prognosis. This study was performed to identify MR imaging biomarkers to forecast the TERT mutation status. METHODS: Pre-operative MRIs of 64/67 genetically confirmed primary GBM...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Promoter Regions, Genetic

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Source

Identifiers

PMID: 28894890
DOI: 10.1007/s00234-017-1920-1

Genes

TERT
MGMT

Provenance

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