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Article

Involvement of DPP9 in gene fusions in serous ovarian carcinoma.

BMC cancer - 11 Sept 2017

Smebye Marianne Lislerud, Agostini Antonio, Johannessen Bjarne, Thorsen Jim, Davidson Ben, Tropé Claes Göran, Heim Sverre, Skotheim Rolf Inge, Micci Francesca

Abstract excerpt

BACKGROUND: A fusion gene is a hybrid gene consisting of parts from two previously independent genes. Chromosomal rearrangements leading to gene breakage are frequent in high-grade serous ovarian carcinomas and have been reported as a common mechanism for inactivating tumor suppressor genes. However, no fusion genes have been repeatedly reported to be recurrent driver events in ovarian carcinogenesis. We combined...

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Topics

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Share to Carcinogenesis
Share to Carcinoma, Ovarian Epithelial

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cystadenocarcinoma, Serous

Share to Dipeptidyl-Peptidases and Tripeptidyl-Peptidases

Share to Gene Fusion

Share to Neoplasms, Glandular and Epithelial

Share to Oncogene Proteins, Fusion

Share to Phosphoprotein Phosphatases

Source

Open in PubMed Open full text

Identifiers

PMID: 28893231
DOI: 10.1186/s12885-017-3625-6
PMCID: PMC5594496

Genes

DPP9
DDA1
MMP27
PLIN3
PLXNB1
WFDC13
ZBTB46

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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