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Article

CDKN2D-WDFY2 is a cancer-specific fusion gene recurrent in high-grade serous ovarian carcinoma.

PLoS genetics - 1 Mar 2014

Kannan Kalpana, Coarfa Cristian, Rajapakshe Kimal, Hawkins Shannon M, Matzuk Martin M, Milosavljevic Aleksandar, Yen Laising

Abstract excerpt

Ovarian cancer is the fifth leading cause of cancer death in women. Almost 70% of ovarian cancer deaths are due to the high-grade serous subtype, which is typically detected only after it has metastasized. Characterization of high-grade serous cancer is further complicated by the significant heterogeneity and genome instability displayed by this cancer. Other than mutations in TP53, which is common to many...

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Share to Gene Expression Regulation, Neoplastic

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Intracellular Signaling Peptides and Proteins

Share to Neoplasm Grading

Share to Oncogene Proteins, Fusion

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Share to Translocation, Genetic

Share to Tumor Suppressor Protein p53

Source

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Identifiers

PMID: 24675677
DOI: 10.1371/journal.pgen.1004216
PMCID: PMC3967933

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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