Article
Novel kinase fusion transcripts found in endometrial cancer.
Scientific reports - 22 Dec 2015
Tamura Ryo, Yoshihara Kosuke, Yamawaki Kaoru, Suda Kazuaki, Ishiguro Tatsuya, Adachi Sosuke, Okuda Shujiro, Inoue Ituro, Verhaak Roel G W, Enomoto Takayuki
Abstract excerpt
Recent advances in RNA-sequencing technology have enabled the discovery of gene fusion transcripts in the transcriptome of cancer cells. However, it remains difficult to differentiate the therapeutically targetable fusions from passenger events. We have analyzed RNA-sequencing data and DNA copy number data from 25 endometrial cancer cell lines to identify potential therapeutically targetable fusion transcripts,...
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