GNAS mutations and heterotopic ossification.

Abstract excerpt

GNAS is a complex imprinted gene encoding the alpha-subunit of the stimulatory heterotrimeric G protein (Gsα). GNAS gives rise to additional gene products that exhibit exclusively maternal or paternal expression, such as XLαs, a large variant of Gsα that shows exclusively paternal expression and is partly identical to the latter. Gsα itself is expressed biallelically in most tissues, although the expression...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to GTP-Binding Protein alpha Subunits, Gs
• Share to Chromogranins
• Share to Cyclic AMP