Article
Haplotype dependent association of rs7927894 (11q13.5) with atopic dermatitis and chronic allergic rhinitis: A study in ECAP cohort.
PloS one - 1 Jan 2017
Ponińska Joanna Kinga, Samoliński Bolesław, Tomaszewska Aneta, Raciborski Filip, Samel-Kowalik Piotr, Walkiewicz Artur, Lipiec Agnieszka, Piekarska Barbara, Krzych-Fałta Edyta, Namysłowski Andrzej, Kostrzewa Grażyna, Pawlik Andrzej, Jasek Monika, Wiśniewski Andrzej, Kuśnierczyk Piotr, Majewski Sławomir, Płoski Rafał
Abstract excerpt
The T allele of rs7927894 (at 11q13.5) was associated with atopic dermatitis and other allergic diseases. Our purpose was to replicate the association with allergic phenotypes and explore the role of rs7927894 in predisposing to persistent allergic rhinitis and atopic asthma. We also wanted to explore if other SNPs at 11q13.5 contributed to effect of rs7927894. We studied patients with atopic dermatitis (N =...
Read the complete abstract on PubMed