The eczema risk variant on chromosome 11q13 (rs7927894) in the population-based ALSPAC cohort: a novel susceptibility factor for asthma and hay fever.

doi:10.1093/hmg/ddr117

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Article

The eczema risk variant on chromosome 11q13 (rs7927894) in the population-based ALSPAC cohort: a novel susceptibility factor for asthma and hay fever.

Human molecular genetics - 15 Jun 2011

Marenholz Ingo, Bauerfeind Anja, Esparza-Gordillo Jorge, Kerscher Tamara, Granell Raquel, Nickel Renate, Lau Susanne, Henderson John, Lee Young-Ae

Abstract excerpt

In a genome-wide association study, a common variant on chromosome 11q13.5 (rs7927894[T]) has been identified as a susceptibility locus for eczema. We aimed to analyze the effect of this risk variant on asthma and hay fever and to determine its impact on the general population level in over 9300 individuals of the prospectively evaluated Avon Longitudinal Study of Parents and Children birth cohort. We demonstrate...

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PMID: 21429916
DOI: 10.1093/hmg/ddr117

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