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Article

Association study on IL4, IL13 and IL4RA polymorphisms in mite-sensitized persistent allergic rhinitis in a Chinese population.

PloS one - 1 Jan 2011

Lu Mei-Ping, Chen Ruo-Xi, Wang Mei-Lin, Zhu Xin-Jie, Zhu Lu-Ping, Yin Min, Zhang Zheng-Dong, Cheng Lei

Abstract excerpt

BACKGROUND: The IL4, IL13, and IL4 receptor α chain (IL4RA) genes are candidate genes for atopic diseases. We hypothesized that the polymorphisms in these genes are associated with persistent allergic rhinitis (PER). OBJECTIVE: To investigate the association of the potential functional polymorphisms in IL4, IL13, and IL4RA with PER induced by house dust mites in a Chinese population. METHODS: Using the TaqMan...

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PMID: 22087298
DOI: 10.1371/journal.pone.0027363
PMCID: PMC3210163

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