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Article

Sumoylation in p27kip1 via RanBP2 promotes cancer cell growth in cholangiocarcinoma cell line QBC939.

BMC molecular biology - 7 Sept 2017

Yang Jun, Liu Yan, Wang Bing, Lan Hongzhen, Liu Ying, Chen Fei, Zhang Ju, Luo Jian

Abstract excerpt

BACKGROUND: Cholangiocarcinoma is one of the deadly disease with poor 5-year survival and poor response to conventional therapies. Previously, we found that p27kip1 nuclear-cytoplasmic translocation confers proliferation potential to cholangiocarcinoma cell line QBC939 and this process is mediated by crm-1. However, no other post-transcriptional regulation was found in this process including sumoylation in...

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Identifiers

PMID: 28882106
DOI: 10.1186/s12867-017-0100-5
PMCID: PMC5590128

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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