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Article

The roles of Notch1 expression in the migration of intrahepatic cholangiocarcinoma

20 May 2013

Abstract excerpt

BACKGROUND: Notch signaling, a critical pathway for tissue development, contributes to tumorigenesis in many tissues; however, the roles of Notch signaling in Intrahepatic Cholangiocarcinoma (ICC) remains unclear. In this study, we evaluated the expression and effects of Notch1 on cell migration in ICC. METHODS: Multiple cellular and molecular approaches were performed including gene transfection, siRNA...

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Share to Cholangiocarcinoma and Gallbladder Cancer Studies
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PMID: 23688168
DOI: 10.1186/1471-2407-13-244

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