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Article

UHRF1 is regulated by miR‐124‐3p and promotes cell proliferation in intrahepatic cholangiocarcinoma

15 Apr 2019

Abstract excerpt

Ubiquitin-like with PHD and ring finger domains 1 (UHRF1) is abnormally overexpressed in multiple cancers and closely correlated with tumor-promoting effects, such as high proliferation. However, how UHRF1 functions in intrahepatic cholangiocarcinoma (ICC) has not yet been determined. Herein, we found that UHRF1 is overexpressed in ICC tissues. Downregulated UHRF1 attenuated the transition of the G1/S cell cycle...

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PMID: 30989656
DOI: 10.1002/jcp.28586

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