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p73 is required for appropriate BMP-induced mesenchymal-to-epithelial transition during somatic cell reprogramming

7 Sept 2017

Abstract excerpt

The generation of induced pluripotent stem cells (iPSCs) by somatic cell reprogramming holds great potential for modeling human diseases. However, the reprogramming process remains very inefficient and a better understanding of its basic biology is required. The mesenchymal-to-epithelial transition (MET) has been recognized as a crucial step for the successful reprogramming of fibroblasts into iPSCs. It has been...

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PMID: 28880267
DOI: 10.1038/cddis.2017.432

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