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SPEN, a new player in primary cilia formation and cell migration in breast cancer

6 Sept 2017

Abstract excerpt

BACKGROUND: The primary cilium is a microtubule-based and nonmotile organelle functioning as a cellular antenna that is involved in the regulation of cell proliferation, differentiation, and migration. In breast cancer cells, the primary cilium is a structure that decreases in incidence with increasing degrees of transformation and may be biologically more important in estrogen receptor (ERα)-negative breast...

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PMID: 28877752
DOI: 10.1186/s13058-017-0897-3

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