Article
High-throughput PCR assay design for targeted resequencing using primerXL.
BMC bioinformatics - 6 Sept 2017
Lefever Steve, Pattyn Filip, De Wilde Bram, Coppieters Frauke, De Keulenaer Sarah, Hellemans Jan, Vandesompele Jo
Abstract excerpt
BACKGROUND: Although the sequencing landscape is rapidly evolving and sequencing costs are continuously decreasing, whole genome sequencing is still too expensive for use on a routine basis. Targeted resequencing of only the regions of interest decreases both costs and the complexity of the downstream data-analysis. Various target enrichment strategies are available, but none of them obtain the degree of coverage...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.