Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

BDNF Val66Met polymorphism influence on striatal blood-level-dependent response to monetary feedback depends on valence and agency.

Neuroscience - 7 Nov 2014

Chumbley J, Späti J, Dörig N, Brakowski J, Grosse Holtforth M, Seifritz E, Spinelli S

Abstract excerpt

Animal work implicates the brain-derived neurotrophic factor (BDNF) in function of the ventral striatum (VS), a region known for its role in processing valenced feedback. Recent evidence in humans shows that BDNF Val66Met polymorphism modulates VS activity in anticipation of monetary feedback. However, it remains unclear whether the polymorphism impacts the processing of self-attributed feedback differently from...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Brain-Derived Neurotrophic Factor
Share to Brain Mapping

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Cerebrovascular Circulation

Share to Frontal Lobe

Share to Neuropsychological Tests

Share to Psychometrics

Share to Reinforcement, Psychology

Share to Self Concept

Source

Identifiers

PMID: 25234319
DOI: 10.1016/j.neuroscience.2014.09.014

Genes

BDNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

BDNF Val66Met polymorphism influence on striatal blood-level-dependent response to monetary feedback depends on valence and agency.PMID 25234319Read ↗

Valence-dependent self-agency is disturbed in depression and anxietySemantic proximity Read ↗

BDNF, relative preference, and reward circuitry responses to emotional communication.Semantic proximity Read ↗

Valence-partitioned learning signals drive choice behavior and phenomenal subjective experience in humansSemantic proximity Read ↗

Genetic polymorphisms of the dopamine and serotonin systems modulate the neurophysiological response to feedback and risk taking in healthy humansSemantic proximity Read ↗

Valence-specific effects of BDNF Val66Met polymorphism on dopaminergic stress and reward processing in humans.Semantic proximity Read ↗

The Interactive Role of Emotion and Expected Efficacy and Reward in Improving Cognitive Control in Patients with DepressionSemantic proximity Read ↗

Music-to My Brain: Modulation of Reward System Activity via Musical NeurofeedbackSemantic proximity Read ↗

Individual differences in extraversion and dopamine genetics predict neural reward responses.Semantic proximity Read ↗

Catechol-O-methyltransferase val158met genotype influences neural processing of reward anticipation.Semantic proximity Read ↗

Distinct neurofunctional alterations during motivational and hedonic processing of natural and monetary rewards in depression – a neuroimaging meta-analysisSemantic proximity Read ↗

BDNF Val66Met polymorphism tunes frontolimbic circuitry during affective contextual learning.Semantic proximity Read ↗

The effects of COMT (Val108/158Met) and DRD4 (SNP -521) dopamine genotypes on brain activations related to valence and magnitude of rewards.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.