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Article

Pan-transcriptome reveals a large accessory genome contribution to gene expression variation in yeast.

Nature genetics - 1 Jun 2024

Caudal Élodie, Loegler Victor, Dutreux Fabien, Vakirlis Nikolaos, Teyssonnière Élie, Caradec Claudia, Friedrich Anne, Hou Jing, Schacherer Joseph

Abstract excerpt

Gene expression is an essential step in the translation of genotypes into phenotypes. However, little is known about the transcriptome architecture and the underlying genetic effects at the species level. Here we generated and analyzed the pan-transcriptome of ~1,000 yeast natural isolates across 4,977 core and 1,468 accessory genes. We found that the accessory genome is an underappreciated driver of...

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Identifiers

PMID: 38778243
DOI: 10.1038/s41588-024-01769-9
PMCID: PMC11176082

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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