Article
Buyanghuanwu Decoction alleviated pressure overload induced cardiac remodeling by suppressing Tgf-β/Smads and MAPKs signaling activated fibrosis.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie - 1 Nov 2017
Chen Huihua, Song Haiyan, Liu Xiao, Tian Jing, Tang Wenzhu, Cao Tongtong, Zhao Pei, Zhang Chen, Guo Wei, Xu Ming, Lu Rong
Abstract excerpt
Buyanghuanwu Decoction (BHD), a traditional Chinese medicine recipe, is a representative prescription for the treatment of qi-deficiency and blood-stasis syndrome. In this study, the effect of BHD on pressure overload induced cardiac remodeling was investigated and possible mechanism underlying was explored. Rats were randomly divided into four groups: sham, transverse aorta constriction (TAC) with saline, TAC...
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