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Upregulation of key genes Eln and Tgfb3 were associated with the severity of cardiac hypertrophy

13 Aug 2022

Abstract excerpt

BACKGROUND: Hypertension-induced cardiac hypertrophy is one of the most common pre-conditions that accompanies heart failure. This study aimed to identify the key pathogenic genes in the disease process. METHODS: GSE18224 was re-analyzed and differentially expressed genes (DEGs) were obtained. Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) analyses were carried out. Networks of...

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PMID: 35964009
DOI: 10.1186/s12864-022-08778-0

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