Article
Nonsteroidal Anti-inflammatory Drug Interaction with Prostacyclin Synthase Protects from Miscarriage.
Scientific reports - 29 Aug 2017
Velez Edwards Digna R, Edwards Todd L, Bray Michael J, Torstenson Eric, Jones Sarah, Shrubsole Martha J, Muff Harvey J, Hartmann Katherine E
Abstract excerpt
This study evaluates the relationship between single nucleotide polymorphisms (SNPs) in nonsteroidal anti-inflammatory drug (NSAID) metabolism and related pathways and spontaneous abortion (SAB, gestation < 20 weeks) risk. Women were enrolled in Right from the Start (2004-2010) prospective cohort. Periconceptional NSAIDs reported through the sixth week of pregnancy were obtained from study interviews. We...
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