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Article

Clinical utility of circulating cell-free DNA in advanced colorectal cancer.

PloS one - 1 Jan 2017

Pereira Allan A Lima, Morelli Maria Pia, Overman Michael, Kee Bryan, Fogelman David, Vilar Eduardo, Shureiqi Imad, Raghav Kanwal, Eng Cathy, Manuel Shanequa, Crosby Shadarra, Wolff Robert A, Banks Kimberly, Lanman Richard, Talasaz AmirAli, Kopetz Scott, Morris Van

Abstract excerpt

BACKGROUND: Circulating cell-free DNA (cfDNA) isolated from the plasma of cancer patients (pts) has been shown to reflect the genomic mutation profile of the tumor. However, physician and patient assessment of clinical utility of these assays in patients with metastatic colorectal cancer (mCRC) has not been previously described. METHODS: Patients were prospectively consented to a prospective genomic matching...

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Identifiers

PMID: 28850629
DOI: 10.1371/journal.pone.0183949
PMCID: PMC5574560

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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