PROSPER Intervention Effects on Adolescents' Alcohol Misuse Vary by GABRA2 Genotype and Age.

doi:10.1007/s11121-017-0751-y

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Article

PROSPER Intervention Effects on Adolescents' Alcohol Misuse Vary by GABRA2 Genotype and Age.

Prevention science : the official journal of the Society for Prevention Research - 1 Jan 2018

Russell Michael A, Schlomer Gabriel L, Cleveland H Harrington, Feinberg Mark E, Greenberg Mark T, Spoth Richard L, Redmond Cleve, Vandenbergh David J

Abstract excerpt

Preventive intervention effects on adolescent alcohol misuse may differ based on genotypes in gene-by-intervention (G x I) interactions, and these G x I interactions may vary as a function of age. The current study uses a novel statistical method, time-varying effect modeling (TVEM), to test an age-varying interaction between a single nucleotide polymorphism in the GABRA2 gene (rs279845) and a preventive...

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PMID: 28185103
DOI: 10.1007/s11121-017-0751-y
PMCID: PMC5552492

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GABRA2

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