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Article

Evidence for an interaction between age at first drink and genetic influences on DSM-IV alcohol dependence symptoms.

Alcoholism, clinical and experimental research - 1 Dec 2009

Agrawal Arpana, Sartor Carolyn E, Lynskey Michael T, Grant Julia D, Pergadia Michele L, Grucza Richard, Bucholz Kathleen K, Nelson Elliot C, Madden Pamela A F, Martin Nicholas G, Heath Andrew C

Abstract excerpt

BACKGROUND: Research suggests that individuals who start drinking at an early age are more likely to subsequently develop alcohol dependence. Twin studies have demonstrated that the liability to age at first drink and to alcohol dependence are influenced by common genetic and environmental factors, however, age at first drink may also environmentally mediate increased risk for alcohol dependence. In this study,...

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Identifiers

PMID: 19764935
DOI: 10.1111/j.1530-0277.2009.01044.x
PMCID: PMC2883563

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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