Article
Performance of an allele-level multi-locus HLA genotype imputation tool in hematopoietic stem cell donors from Quebec.
Immunity, inflammation and disease - 1 Dec 2017
Ferradji Abdelhakim, D'Souza Yasmin, Saw Chee Loong, Oualkacha Karim, Richard Lucie, Sapir-Pichhadze Ruth
Abstract excerpt
INTRODUCTION: Donor-recipient HLA compatibility is an important determinant of transplant outcomes. Allele-group to allele-level imputations help assign HLA genotypes when allele-level genotypes are not available during donor selection. METHODS: We evaluated the performance of HaploStats, an allele-level multi-locus HLA genotype imputation tool from the National Marrow Donor Program, in a cross-sectional study...
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