Article
Polymorphisms associated with resistance to protease inhibitors in naïve patients infected with hepatitis C virus genotype 1 in Argentina: Low prevalence of Q80K.
Virus research - 15 Aug 2017
Martínez Alfredo P, Culasso Andrés C A, Pérez Paula S, Romano Vanesa, Campos Rodolfo H, Ridruejo Ezequiel, García Gabriel, Di Lello Federico A
Abstract excerpt
Incorporation of direct acting antivirals (DAA) in the treatment of Hepatitis C Virus (HCV) significantly increases sustained virologic response rates. However, despite the greater potency offered by these antivirals, drug resistance plays a key role in patients with failure to DAA. Nevertheless, there is no information about the prevalence of resistance-associated substitutions (RASs) in Argentina. The aim of...
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