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Article

Protease inhibitor resistance mutations in untreated Brazilian patients infected with HCV: novel insights about targeted genotyping approaches.

Journal of medical virology - 1 Oct 2014

de Carvalho Isabel M V G, Alves Rafael, de Souza Polyana A Vasconcelos-Medeiros, da Silva Edvaldo F, Mazo Daniel, Carrilho Flair J, Queiroz Artur T L, Pessoa Mário G

Abstract excerpt

Several new direct-acting antiviral (DAA) drugs are being developed or are already approved for the treatment of chronic hepatitis C virus (HCV) infection. HCV variants presenting drug-resistant phenotypes were observed both in vitro and during clinical trials. The aim of this study was to characterize amino acid changes at positions previously associated with resistance in the NS3 protease in untreated Brazilian...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Drug Resistance, Viral

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Source

Identifiers

PMID: 25042789
DOI: 10.1002/jmv.24015

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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