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Article

Transporter genes ABCG2 rs2231142 and ABCB1 rs1128503 polymorphisms and atorvastatin response in Chilean subjects.

Journal of clinical pharmacy and therapeutics - 1 Feb 2018

Prado Y, Zambrano T, Salazar L A

Abstract excerpt

WHAT IS KNOWN AND OBJECTIVE: Statins are first-line therapy for reducing high cholesterol levels. However, response to these drugs shows high interindividual variability. We aimed to investigate the influence of two single nucleotide polymorphisms (SNP) (ABCB1 rs1128503 and ABCG2 rs2231142) in the ABC transporter genes on response to short-term low-dose atorvastatin in Chilean hypercholesterolaemic patients....

Read the complete abstract on PubMed

Topics

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Atorvastatin

Share to ATP Binding Cassette Transporter, Subfamily B

Share to ATP Binding Cassette Transporter, Subfamily G, Member 2

Share to Cholesterol, LDL

Share to Hypercholesterolemia

Share to Lipids

Share to Neoplasm Proteins

Share to Triglycerides

Source

Identifiers

PMID: 28833323
DOI: 10.1111/jcpt.12607

Genes

ABCB1
ABCG2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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