Article
Analysis of the Association of Nonsynonymous Polymorphisms in ADH Genes with Hazardous Drinking in HIV-1-Positive Individuals.
Alcoholism, clinical and experimental research - 1 Nov 2017
Wolf Jonas Michel, Simon Daniel, Béria Jorge Umberto, Tietzmann Daniela Cardoso, Stein Airton Tetelbom, Lunge Vagner Ricardo
Abstract excerpt
BACKGROUND: Hazardous drinking (HD) is a serious health problem in people infected with human immunodeficiency virus type 1 (HIV-1). Single nucleotide polymorphisms (SNPs) in alcohol dehydrogenase (ADH) genes have been associated with HD in different populations, but there were no data about this in HIV-1-positive individuals. This study investigated the association of 4 nonsynonymous SNPs in ADH genes (Arg48His...
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