Article
CYP260B1 acts as 9α-hydroxylase for 11-deoxycorticosterone.
Steroids - 1 Nov 2017
Litzenburger Martin, Bernhardt Rita
Abstract excerpt
Steroids and their oxyfunctionalized counterparts are valuable compounds for the pharmaceutical industry; however, the regio- and stereoselective introduction of oxygen is a challenging task for the synthetic chemistry. Thus, cytochromes P450 play an important role for the functionalization of steroidal compounds. In this study, we elucidated the main product of 11-deoxycorticosterone conversion formed by...
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