Article
Scalable Lentiviral Vector Production Using Stable HEK293SF Producer Cell Lines
22 Aug 2017
Abstract excerpt
Lentiviral vectors (LV) represent a key tool for gene and cell therapy applications. The production of these vectors in sufficient quantities for clinical applications remains a hurdle, prompting the field toward developing suspension processes that are conducive to large-scale production. This study describes a LV production strategy using a stable inducible producer cell line. The HEK293 cell line employed...