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Article

Role of IL-4 gene polymorphisms in HBV-related hepatocellular carcinoma in a Chinese population.

PloS one - 1 Jan 2014

Lu Yu, Wu Zhitong, Peng Qiliu, Ma Liping, Zhang Xiaolian, Zhao Jiangyang, Qin Xue, Li Shan

Abstract excerpt

BACKGROUND: Interleukin-4 (IL-4) is best known as an important mediator and modulator of immune and inflammatory responses. Hepatocellular carcinoma (HCC) is a typical inflammation-related cancer, and genetic variations in the IL-4 gene may be associated with the risk of hepatitis B virus (HBV)-related HCC. However, few studies have been conducted on their association. OBJECTIVES: To clarify the effects of IL-4...

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Identifiers

PMID: 25295591
DOI: 10.1371/journal.pone.0110061
PMCID: PMC4190355

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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