Article
Role of IL-4 gene polymorphisms in HBV-related hepatocellular carcinoma in a Chinese population.
PloS one - 1 Jan 2014
Lu Yu, Wu Zhitong, Peng Qiliu, Ma Liping, Zhang Xiaolian, Zhao Jiangyang, Qin Xue, Li Shan
Abstract excerpt
BACKGROUND: Interleukin-4 (IL-4) is best known as an important mediator and modulator of immune and inflammatory responses. Hepatocellular carcinoma (HCC) is a typical inflammation-related cancer, and genetic variations in the IL-4 gene may be associated with the risk of hepatitis B virus (HBV)-r...
Topics
- Adult
- Asian People
- Base Sequence
- Carcinoma, Hepatocellular
- Case-Control Studies
- Female
- Genetic Predisposition to Disease
- Genotyping Techniques
- Haplotypes
- Hepatitis B virus
- Humans
- Interleukin-4
- Liver Neoplasms
- Male
- Middle Aged
- Polymorphism, Single Nucleotide